SCHEMBL22448871

SCHEMBL22448871

CCCC1COC(C2CCC(c3ccc(-c4cc(F)c(OC(F)(F)F)c(F)c4)c(F)c3)CC2)OC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18314901 0.89 CYP2C9 (0.30) CYP2C9
SCHEMBL17175207 0.89 CYP2C9 (0.37) CYP2C9
SCHEMBL18310497 0.88
SCHEMBL12626489 0.88
SCHEMBL15744801 0.87
SCHEMBL12621626 0.86
SCHEMBL15744238 0.84 CYP2C9 (0.31) CYP2C9
SCHEMBL7851837 0.84 CYP2C9 (0.34) CYP2C9
SCHEMBL12625329 0.84 GRM2 (0.32)
SCHEMBL6460074 0.83 CYP2C9 (0.32) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3712230-A1 LIQUID CRYSTAL COMPOUNDS Merck Patent GmbH (DE) 2020-09-23 EP disclosed