Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15036987 | 1.00 | PPARG (0.45) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL15037344 | 1.00 | PPARG (0.45) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL15037129 | 0.90 | PPARG (0.55) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL15091916 | 0.90 | PPARG (0.55) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL15037347 | 0.89 | PPARG (0.49) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL22449059 | 0.89 | PPARG (0.49) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL15037341 | 0.89 | PPARG (0.49) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL22449136 | 0.88 | PPARG (0.49) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL22449153 | 0.88 | PPARG (0.49) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL15037343 | 0.88 | PPARG (0.49) | PPARGPPARAITGB1ITGA4ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |