Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.80 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1378887 | 0.89 | HRH3 (1.00) | HRH3SCN9A | |
| SCHEMBL1377358 | 0.88 | HRH3 (0.89) | HRH3SCN9A | |
| SCHEMBL1377485 | 0.85 | HRH3 (0.75) | HRH3SCN9A | |
| SCHEMBL1381783 | 0.84 | HRH3 (0.89) | HRH3SCN9A | |
| SCHEMBL1379507 | 0.84 | HRH3 (0.76) | HRH3SCN9A | |
| SCHEMBL1381698 | 0.83 | HRH3 (0.74) | HRH3SCN9A | |
| SCHEMBL1380440 | 0.83 | HRH3 (0.74) | HRH3SCN9A | |
| SCHEMBL1378054 | 0.83 | HRH3 (0.73) | HRH3SCN9A | |
| SCHEMBL1377618 | 0.82 | HRH3 (0.69) | HRH3SCN9A | |
| SCHEMBL1377924 | 0.82 | HRH3 (1.00) | HRH3SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805166-B1 | QUINOLINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2011-07-27 | — | — | EP | claimed |