Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22451258 | 0.93 | NPC1 (0.39) | NPC1RAB9APOLBPLK1KDM4E | |
| SCHEMBL21261974 | 0.93 | NPC1 (0.39) | NPC1RAB9APOLBPLK1KDM4E | |
| SCHEMBL21262068 | 0.93 | NPC1 (0.39) | NPC1RAB9APOLBPLK1KDM4E | |
| SCHEMBL19199350 | 0.93 | NPC1 (0.39) | NPC1RAB9APOLBPLK1KDM4E | |
| SCHEMBL22549199 | 0.90 | NPC1 (0.37) | NPC1RAB9APOLBPLK1KDM4E | |
| SCHEMBL24345953 | 0.89 | NPC1 (0.35) | NPC1RAB9APOLBPLK1KDM4E | |
| SCHEMBL22451251 | 0.89 | NPC1 (0.33) | NPC1RAB9APOLBPLK1KDM4E | |
| SCHEMBL22451177 | 0.86 | TSHR (0.34) | NPC1RAB9APOLBPLK1 | |
| SCHEMBL22451353 | 0.86 | TSHR (0.37) | NPC1RAB9APOLBPLK1 | |
| SCHEMBL22451189 | 0.85 | APP (0.34) | NPC1RAB9APOLBPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712138-A1 | BENZOTRIAZOLE COMPOUND | Miyoshi Oil & Fat Co., Ltd. (JP) | 2020-09-23 | — | — | EP | disclosed |