Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19803592 | 1.00 | CALCRL (0.49) | CALCRLRIPK1 | |
| SCHEMBL22441102 | 1.00 | CALCRL (0.49) | CALCRLRIPK1 | |
| SCHEMBL22451404 | 0.89 | CALCRL (0.53) | CALCRLRIPK1 | |
| SCHEMBL20843447 | 0.89 | CALCRL (0.53) | CALCRLRIPK1 | |
| SCHEMBL19803596 | 0.89 | CALCRL (0.53) | CALCRLRIPK1 | |
| SCHEMBL20835829 | 0.87 | CALCRL (0.47) | CALCRLRIPK1 | |
| SCHEMBL20843505 | 0.86 | CALCRL (0.54) | CALCRL | |
| SCHEMBL20835821 | 0.83 | CALCRL (0.50) | CALCRL | |
| SCHEMBL22451425 | 0.83 | CALCRL (0.50) | CALCRL | |
| SCHEMBL20835819 | 0.83 | CALCRL (0.50) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995084-B2 | Pyrrolidine derivative | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2021-05-04 | — | — | US | disclosed |
| US-20200299273-A1 | PYRROLIDINE DERIVATIVE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299273-A1 | PYRROLIDINE DERIVATIVE | CALCRL, NPY1R, GRPR | CALCRL 1/4885RIPK1 1917/4885 |
| US-10995084-B2 | Pyrrolidine derivative | CALCRL, NPY1R, GRPR | CALCRL 1/4885RIPK1 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.