Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452493 | 0.90 | DHODH (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22452621 | 0.89 | CNR2 (0.54) | CNR2LMNAHIF1AALDH1A1MEN1 | |
| SCHEMBL22453725 | 0.89 | CNR2 (0.56) | CNR2LMNAHIF1ADHODHALDH1A1 | |
| SCHEMBL22452612 | 0.85 | MAPT (0.46) | LMNAHIF1ACYP1A2CYP2C9MAPT | |
| SCHEMBL22453427 | 0.84 | CNR2 (0.57) | CNR2HIF1ADHODHALDH1A1MEN1 | |
| SCHEMBL22452622 | 0.84 | CNR2 (0.60) | CNR2POLBHIF1AALDH1A1MEN1 | |
| SCHEMBL22453548 | 0.83 | CNR2 (0.56) | CNR2LMNAPOLBHIF1ADHODH | |
| SCHEMBL22453117 | 0.83 | CNR2 (0.53) | CNR2HIF1ADHODHALDH1A1MEN1 | |
| SCHEMBL22452895 | 0.82 | CNR2 (0.57) | CNR2LMNAPOLBHIF1ADHODH | |
| SCHEMBL22452654 | 0.81 | CNR2 (0.57) | CNR2HIF1AALDH1A1MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |