Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452943 | 1.00 | AKT1 (0.47) | AKT1OPRD1OPRM1OPRK1HDAC3 | |
| SCHEMBL22768342 | 0.93 | AKT1 (0.46) | AKT1OPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL28385639 | 0.93 | AKT1 (0.46) | AKT1OPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL17003582 | 0.93 | AKT1 (0.46) | AKT1OPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL18224261 | 0.93 | AKT1 (0.46) | AKT1OPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL28385636 | 0.93 | AKT1 (0.46) | AKT1OPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL25871102 | 0.93 | AKT1 (0.46) | AKT1OPRD1OPRM1OPRK1HDAC3 | |
| SCHEMBL25053006 | 0.92 | AKT1 (0.45) | AKT1OPRD1OPRM1OPRK1HDAC3 | |
| SCHEMBL20345224 | 0.92 | AKT1 (0.45) | AKT1OPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL20041046 | 0.92 | AKT1 (0.45) | AKT1OPRD1OPRM1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035787-A2 | CLAUDIN-6 ANTIBODIES AND CONJUGATES THEREOF AND USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-02-15 | — | — | WO | disclosed |
| WO-2020191342-A1 | CLAUDIN-6 ANTIBODIES AND DRUG CONJUGATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020191344-A1 | CLAUDIN-6 BISPECIFIC ANTIBODIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-09-24 | — | — | WO | disclosed |