Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | BIRC3 | Q13489 | 4/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209958 | 0.96 | XIAP (0.62) | XIAPKMT2ALMNAGAAMAPT | |
| SCHEMBL18494245 | 0.96 | XIAP (0.62) | XIAPKMT2ALMNAGAAMAPT | |
| SCHEMBL2209986 | 0.96 | XIAP (0.62) | XIAPKMT2ALMNAGAAMAPT | |
| SCHEMBL2212223 | 0.95 | XIAP (0.61) | XIAPKMT2ALMNAGAAMAPT | |
| SCHEMBL2211890 | 0.95 | XIAP (0.61) | XIAPKMT2ALMNAGAAMAPT | |
| SCHEMBL2583934 | 0.93 | XIAP (0.57) | XIAPKMT2ALMNAGAAMAPT | |
| SCHEMBL2209871 | 0.93 | XIAP (0.57) | XIAPKMT2ALMNAGAAMAPT | |
| SCHEMBL2212272 | 0.90 | XIAP (0.64) | XIAPKMT2AALDH1A1TSHRHPGD | |
| SCHEMBL2212263 | 0.90 | XIAP (0.64) | XIAPKMT2AALDH1A1TSHRHPGD | |
| SCHEMBL14174413 | 0.90 | XIAP (0.57) | XIAPKMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099769-B1 | 6-OXO.-1, 6-DIHYDROPYRIMIDIN-2-YLS IN THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-07-27 | — | — | EP | claimed |