Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.77 |
| ▸ | FABP1 | P07148 | 1/20 | 0.69 |
| ▸ | FABP6 | P51161 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NOS1 | P29475 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | GPR39 | O43194 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL589266 | 0.88 | CXCR4 (1.00) | CXCR4FABP1FABP6KDM4ENPC1 | |
| SCHEMBL29351380 | 0.88 | CXCR4 (1.00) | CXCR4FABP1FABP6KDM4ENPC1 | |
| SCHEMBL19868462 | 0.83 | CXCR4 (0.82) | CXCR4FABP1FABP6KDM4ENPC1 | |
| SCHEMBL29580306 | 0.83 | CXCR4 (0.82) | CXCR4FABP1FABP6KDM4ENPC1 | |
| SCHEMBL10055030 | 0.82 | CXCR4 (0.89) | CXCR4FABP1FABP6KDM4ENPC1 | |
| SCHEMBL29664808 | 0.82 | FABP1 (1.00) | CXCR4FABP1FABP6KDM4ENPC1 | |
| SCHEMBL2230559 | 0.82 | FABP1 (1.00) | CXCR4FABP1FABP6KDM4ENPC1 | |
| SCHEMBL27585010 | 0.80 | FABP1 (0.96) | CXCR4FABP1FABP6KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL4696844 | 0.80 | FABP1 (0.96) | CXCR4FABP1FABP6KDM4ENPC1 | |
| Fluoride SCHEMBL28270594 | 0.80 | FABP1 (0.96) | CXCR4FABP1FABP6KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200299262-A1 | ARYL-SUBSTITUTED DIHYDROQUINOLINONES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | EPIGENETIX, INC. | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299262-A1 | ARYL-SUBSTITUTED DIHYDROQUINOLINONES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | BRPF3, BRD4, BRDT | CXCR4 2311/4885FABP1 2366/4885FABP6 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.