Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22461618 | 1.00 | NAMPT (0.65) | NAMPTMITFFFAR1MEN1KMT2A | |
| SCHEMBL243401 | 0.94 | CYP17A1 (0.56) | NAMPTMITFMEN1KMT2AEPHX2 | |
| SCHEMBL21661749 | 0.94 | NAMPT (0.72) | NAMPTMEN1KMT2ACYP17A1NPC1 | |
| SCHEMBL17526122 | 0.91 | NAMPT (0.73) | NAMPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2062613 | 0.89 | NAMPT (0.67) | NAMPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8770870 | 0.89 | NAMPT (0.67) | NAMPTFFAR1MEN1KMT2ACYP17A1 | |
| SCHEMBL3360413 | 0.89 | CYP17A1 (0.63) | NAMPTEPHX2NR1H4CYP17A1MAPT | |
| SCHEMBL8773493 | 0.89 | NAMPT (0.67) | NAMPTMEN1KMT2ANR1H4CYP17A1 | |
| SCHEMBL22440673 | 0.88 | STAT3 (0.57) | NAMPTMITFFFAR1MEN1KMT2A | |
| SCHEMBL22440689 | 0.88 | STAT3 (0.57) | NAMPTMITFFFAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200298194-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200298194-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | ANXA6, ANXA1, ANXA11 | NAMPT 1706/4885MITF 2173/4885FFAR1 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.