⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22280906 | 0.83 | MAPK1 (0.36) | — | |
| SCHEMBL22281266 | 0.81 | MAPK1 (0.35) | — | |
| SCHEMBL22280903 | 0.79 | MAPK1 (0.36) | — | |
| SCHEMBL22281229 | 0.78 | MAPK1 (0.38) | — | |
| SCHEMBL22280905 | 0.76 | BRD4 (0.37) | — | |
| SCHEMBL22281268 | 0.76 | PDE2A (0.37) | — | |
| SCHEMBL22281269 | 0.76 | BRD4 (0.39) | — | |
| SCHEMBL22280890 | 0.76 | MAPK1 (0.37) | — | |
| SCHEMBL22461373 | 0.76 | MAPK1 (0.37) | — | |
| SCHEMBL22280899 | 0.74 | MEN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001590-B2 | Pyrazolopyrimidine derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| US-20200299299-A1 | NEW PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2020-09-24 | — | — | US | disclosed |