Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PAX3 | P23760 | 1/20 | 0.34 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001689 | 0.85 | KDM4E (0.48) | KDM4ETSHRMEN1KMT2ANOS1 | |
| SCHEMBL22765060 | 0.85 | KDM4E (0.48) | KDM4ETSHRMEN1KMT2ANOS1 | |
| SCHEMBL15763710 | 0.84 | CDK5 (0.48) | KDM4ETSHRMEN1KMT2ANOS1 | |
| SCHEMBL22091499 | 0.82 | KDM4E (0.47) | KDM4ETSHRMEN1KMT2ANOS1 | |
| SCHEMBL18349588 | 0.81 | KDM4E (0.46) | KDM4ETSHRMEN1KMT2ANOS1 | |
| SCHEMBL22571148 | 0.81 | MEN1 (0.52) | KDM4ETSHRMEN1KMT2ANOS1 | |
| SCHEMBL3457921 | 0.80 | MEN1 (0.50) | KDM4ETSHRMEN1KMT2AFGFR1 | |
| SCHEMBL22571139 | 0.80 | KDM4E (0.47) | KDM4ETSHRMEN1KMT2ANOS1 | |
| SCHEMBL22083756 | 0.80 | KDM4E (0.47) | KDM4ETSHRMEN1KMT2ANOS1 | |
| Hydrochloric Acid SCHEMBL31087990 | 0.78 | MEN1 (0.48) | KDM4ETSHRMEN1KMT2AFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191252-A1 | TECHNOLOGIES USEFUL FOR OLIGONUCLEOTIDE PREPARATION | WAVE LIFE SCIENCES LTD. (SG) | 2020-09-24 | — | — | WO | disclosed |