SCHEMBL22462062

SCHEMBL22462062

CCCCC1(CCCC)c2ccccc2-c2ccc(C(=O)C(C)C)cc21

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 18/20 0.43
▸ APEX1 P27695 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.38
▸ DBH P09172 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23805902 0.86 PDK2 (0.41) PDK2APEX1KDM4E
SCHEMBL16550638 0.85 PDK2 (0.53) PDK2APEX1
SCHEMBL23805933 0.84 PDK2 (0.44) PDK2APEX1
SCHEMBL18235863 0.84 PDK2 (0.45) PDK2APEX1
SCHEMBL23805907 0.83 APEX1 (0.47) PDK2APEX1
SCHEMBL4822886 0.82 PDK2 (0.43) PDK2APEX1
SCHEMBL18682726 0.82 APEX1 (0.42) PDK2APEX1
SCHEMBL14768863 0.82 PDK2 (0.45) PDK2APEX1
SCHEMBL31282446 0.81 SMN1; SMN2 (0.41) PDK2APEX1KDM4EGAA
SCHEMBL21025023 0.81 PDK2 (0.45) PDK2APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3715381-B1 DIBUTYLFLUORENE DERIVATIVE AND APPLICATION THEREOF AS PHOTOINITIATOR HUIZHOU HUAHONG NEW MAT CO LTD (CN) 2024-06-12 — — EP disclosed
US-11560362-B2 Dibutylfluorene derivative and application thereof as photoinitiator HUIZHOU HUAHONG NEW MATERIAL CO., LTD. (CN) 2023-01-24 — — US disclosed
US-11560362-B2 Dibutylfluorene derivative and application thereof as photoinitiator HUIZHOU HUAHONG NEW MATERIAL CO., LTD. (CN) 2023-01-24 — — US disclosed
US-20200385359-A1 DIBUTYLFLUORENE DERIVATIVE AND APPLICATION THEREOF AS PHOTOINITIATOR HUIZHOU HUAHONG NEW MATERIAL CO., LTD. (CN) 2020-12-10 — — US disclosed
US-20200385359-A1 DIBUTYLFLUORENE DERIVATIVE AND APPLICATION THEREOF AS PHOTOINITIATOR HUIZHOU HUAHONG NEW MATERIAL CO., LTD. (CN) 2020-12-10 — — US disclosed
EP-3715381-A1 DIBUTYLFLUORENE DERIVATIVE AND APPLICATION THEREOF AS PHOTOINITIATOR Huizhou Huahong New Material Co. Ltd. (CN) 2020-09-30 — — EP disclosed
CN-108117616-B Dibutylfluorenyl derivative and its application as photoinitiator 惠州市华泓新材料股份有限公司 2019-08-09 — — CN disclosed
CN-108117616-A Dibutylfluorenyl derivative and its application as photoinitiator 惠州市华泓新材料股份有限公司 2018-06-05 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11560362-B2 Dibutylfluorene derivative and application thereof as photoinitiator NOTUM, FDFT1, DDT PDK2 471/4885APEX1 1702/4885KDM4E 2254/4885
US-20200385359-A1 DIBUTYLFLUORENE DERIVATIVE AND APPLICATION THEREOF AS PHOTOINITIATOR NOTUM, FDFT1, DDT PDK2 471/4885APEX1 1702/4885KDM4E 2254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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