⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636424 | 0.88 | — | — | |
| SCHEMBL11507036 | 0.78 | — | — | |
| SCHEMBL3823153 | 0.78 | — | — | |
| SCHEMBL1149487 | 0.78 | — | — | |
| SCHEMBL3828947 | 0.78 | — | — | |
| SCHEMBL98 | 0.72 | — | — | |
| SCHEMBL992304 | 0.72 | — | — | |
| SCHEMBL6704332 | 0.72 | TP53 (0.31) | — | |
| SCHEMBL1698883 | 0.67 | — | — | |
| SCHEMBL6068389 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240255495-A1 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2024-08-01 | — | — | US | claimed |
| EP-3823975-B1 | PROCESS FOR PREPARATION OF O, O-DIMETHYL PHOSPHORAMIDOTHIOATE AND N-(METHOXY-METHYLSULFANYLPHOSPHORYL) ACETAMIDE | ARYSTA LIFESCIENCE INC (US) | 2024-06-12 | — | — | EP | claimed |
| US-20230002424-A1 | PROCESS FOR PREPARATION OF THIOPHOSPHORYL CHLORIDE AND ACEPHATE | UPL LTD (IN) | 2023-01-05 | — | — | US | claimed |
| WO-2022232195-A2 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-11-03 | — | — | WO | claimed |
| CN-114957318-A | Method for producing acephate | UPL有限公司 | 2022-08-30 | — | — | CN | claimed |
| US-11198700-B2 | Process for preparation of O,O dimethyl phosphoramidothioate and N-(methoxymethylsulfanylphosphoryl) acetamide | ARYSTA LIFESCIENCE INC (US) | 2021-12-14 | — | — | US | claimed |
| EP-3823975-A1 | PROCESS FOR PREPARATION OF O, O-DIMETHYL PHOSPHORAMIDOTHIOATE AND N-(METHOXY-METHYLSULFANYLPHOSPHORYL) ACETAMIDE | Arysta Lifescience Inc. (US) | 2021-05-26 | — | — | EP | claimed |
| WO-2021074775-A1 | PROCESS FOR PREPARATION OF THIOPHOSPHORYL CHLORIDE AND ACEPHATE | UPL LIMITED (IN) | 2021-04-22 | — | — | WO | claimed |
| US-20200255459-A1 | PROCESS FOR PREPARATION OF O,O DIMETHYL PHOSPHORAMIDOTHIOATE AND N-(METHOXYMETHYLSULFANYLPHOSPHORYL) ACETAMIDE | ARYSTA LIFESCIENCE INC | 2020-08-13 | — | — | US | claimed |
| US-10669295-B2 | Process for preparation of O,O-dimethyl phosphoramidothioate and N-(methoxy-methylsulfanylphosphoryl) acetamide | ARYSTA LIFESCIENCE INC. (US) | 2020-06-02 | — | — | US | claimed |
| US-8999960-B2 | Oxidized thiophospholipid compounds and uses thereof | VASCULAR BIOGENICS LTD. (IL) | 2015-04-07 | — | — | US | claimed |
| US-20110195937-A1 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-08-11 | — | — | US | claimed |
| EP-2348864-A2 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | Vascular Biogenics Ltd. (IL) | 2011-08-03 | — | — | EP | claimed |
| WO-2010041242-A2 | OXIDIZED THIOPHOSPHOLIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2010-04-15 | — | — | WO | claimed |
| US-5081272-A | PROCESS FOR PREPARATION OF PHOSPHORODICHLOROTHIOATES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | claimed |
| EP-0307501-A1 | Process for preparing phosphorothioates and phosphates and phosphonothioates and phosphonates | DOWELANCO (US) | 1989-03-22 | — | — | EP | claimed |
| US-4727178-A | Process for preparing phosphorodichloridothiolate | STAUFFER CHEMICAL CO. (US) | 1988-02-23 | — | — | US | claimed |
| EP-0019700-B1 | PROCESS FOR THE PREPARATION OF PHOSPHORCHLORIDE THIOLATES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-06-08 | — | — | EP | claimed |
| EP-0019700-A2 | Process for the preparation of phosphorchloride thiolates | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1980-12-10 | — | — | EP | claimed |
| US-4056581-A | Process for the preparation of phosphorodichloridothiolates | ROHM AND HAAS COMPANY (US) | 1977-11-01 | — | — | US | claimed |