Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22468357 | 0.97 | BRAF (0.60) | BRAFRAF1 | |
| SCHEMBL22488157 | 0.90 | BRAF (0.78) | BRAFRAF1 | |
| SCHEMBL22488128 | 0.90 | BRAF (0.78) | BRAFRAF1 | |
| SCHEMBL22468562 | 0.90 | BRAF (0.78) | BRAFRAF1 | |
| SCHEMBL30291747 | 0.87 | BRAF (0.72) | BRAFRAF1 | |
| SCHEMBL22468390 | 0.87 | BRAF (0.72) | BRAFRAF1 | |
| SCHEMBL22612948 | 0.86 | RAF1 (0.62) | BRAFRAF1 | |
| SCHEMBL22468581 | 0.86 | RAF1 (0.49) | BRAFRAF1 | |
| SCHEMBL29358797 | 0.86 | RAF1 (0.49) | BRAFRAF1 | |
| SCHEMBL22488500 | 0.85 | BRAF (0.70) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941922-A1 | INHIBITORS OF RAF KINASES | Kinnate Biopharma Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| CN-113874381-A | Inhibitors of RAF kinase | 金耐特生物制药公司 | 2021-12-31 | — | — | CN | disclosed |
| WO-2020198058-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020198058-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2020-10-01 | — | — | WO | disclosed |