Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 9/20 | 0.72 |
| ▸ | LCLAT1 | Q6UWP7 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899883 | 0.99 | STAT3 (0.73) | STAT3LCLAT1LMNAKDM4EMEN1 | |
| SCHEMBL1900802 | 0.90 | STAT3 (0.70) | STAT3LMNAKDM4EMEN1HTT | |
| SCHEMBL1901062 | 0.88 | STAT3 (0.77) | STAT3LCLAT1LMNAKDM4EMEN1 | |
| SCHEMBL1898078 | 0.87 | STAT3 (0.74) | STAT3LMNAKDM4EMEN1HTT | |
| SCHEMBL1901042 | 0.86 | STAT3 (0.73) | STAT3LCLAT1LMNAKDM4EMEN1 | |
| SCHEMBL1898201 | 0.85 | STAT3 (0.81) | STAT3LCLAT1LMNAKDM4EMEN1 | |
| SCHEMBL1899737 | 0.85 | STAT3 (0.72) | STAT3LMNAKDM4EMEN1HTT | |
| SCHEMBL1905449 | 0.85 | STAT3 (0.84) | STAT3LMNAKDM4EMEN1HTT | |
| SCHEMBL1899842 | 0.85 | STAT3 (0.63) | STAT3LMNAKDM4EMEN1HTT | |
| SCHEMBL1906040 | 0.85 | STAT3 (0.73) | STAT3LMNAKDM4EMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020196327-A1 | PRODUCTION METHOD OF QUINOLINECARBOXAMIDE DERIVATIVE OR PRODUCTION INTERMEDIATE THEREOF | 株式会社ヤクルト本社 | 2020-10-01 | — | — | WO | disclosed |