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SCHEMBL22474467

SCHEMBL22474467

Cc1ccc(P(c2ccc(C)cc2)c2cccc3c2O[C@@H]2CCC[C@H](C3)Oc3c(cccc3P(c3ccccc3)c3ccccc3)C2)cc1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ DRD1 P21728 2/20 0.38
▸ TOP1 P11387 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22474496 0.96 DRD1 (0.32) DRD1TOP1
SCHEMBL22474509 0.96 DRD1 (0.32) DRD1TOP1
SCHEMBL20822406 0.92 DRD1 (0.40) DRD1TOP1
SCHEMBL20988606 0.92 DRD1 (0.40) DRD1TOP1
SCHEMBL22474508 0.92 DRD1 (0.40) DRD1TOP1
SCHEMBL21703407 0.92 DRD1 (0.40) DRD1TOP1
SCHEMBL22474493 0.92 DRD1 (0.40) DRD1TOP1
SCHEMBL22474464 0.91 DRD1 (0.37) DRD1TOP1
SCHEMBL22474474 0.87 DRD1 (0.42) DRD1
SCHEMBL22474511 0.86 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2876108-B1 COMPOUNDS OF CHIRAL AROMATIC SPIROKETAL DIPHOSPHINE LIGANDS, PREPARATION METHODS AND USES THEREOF SHANGHAI INST ORGANIC CHEMISTRY CAS (CN) 2020-09-30 — — EP disclosed