Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.37 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20610935 | 0.91 | SLC28A1 (0.39) | POLBHSD17B10MEN1USP2KMT2A | |
| SCHEMBL16144608 | 0.89 | POLB (0.40) | POLBHSD17B10MEN1USP2KMT2A | |
| SCHEMBL16644423 | 0.89 | POLB (0.40) | POLBHSD17B10MEN1USP2KMT2A | |
| SCHEMBL20611194 | 0.88 | POLB (0.40) | POLBHSD17B10MEN1USP2KMT2A | |
| SCHEMBL23808332 | 0.84 | SLC28A1 (0.43) | POLBHSD17B10SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL16108405 | 0.84 | SLC28A1 (0.43) | POLBHSD17B10SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL16108403 | 0.84 | SLC28A1 (0.43) | POLBHSD17B10SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL23808336 | 0.84 | P2RY6 (0.40) | POLBHSD17B10SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL20611188 | 0.83 | TDP1 (0.37) | POLBHSD17B10MEN1USP2KMT2A | |
| SCHEMBL15841051 | 0.80 | POLB (0.43) | POLBHSD17B10MEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935303-B1 | 4'-FLUORO-NUCLEOSIDES, 4'-FLUORO-NUCLEOTIDES AND ANALOGS THEREOF FOR THE TREATMENT OF HCV | JANSSEN BIOPHARMA INC (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-3160476-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTION | JANSSEN BIOPHARMA INC (US) | 2020-09-30 | — | — | EP | disclosed |