Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 15/20 | 0.53 |
| ▸ | FER | P16591 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930598 | 1.00 | SYK (0.53) | SYKFERBTKTYK2HDAC4 | |
| SCHEMBL29949698 | 1.00 | SYK (0.53) | SYKFERBTKTYK2HDAC4 | |
| SCHEMBL16751349 | 0.92 | SYK (0.56) | SYKFERBTKTYK2 | |
| SCHEMBL1990177 | 0.90 | SYK (0.59) | SYKFERBTKTYK2 | |
| SCHEMBL1990162 | 0.90 | SYK (0.59) | SYKFERBTKTYK2 | |
| SCHEMBL21032755 | 0.87 | SYK (0.71) | SYKFERBTKTYK2 | |
| SCHEMBL22475414 | 0.87 | SYK (0.71) | SYKFERBTKTYK2 | |
| SCHEMBL29949466 | 0.87 | SYK (0.71) | SYKFERBTKTYK2 | |
| SCHEMBL14930565 | 0.87 | SYK (0.71) | SYKFERBTKTYK2 | |
| SCHEMBL12605543 | 0.86 | SYK (0.51) | SYKFERBTKTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489236-B1 | PROCESS FOR THE PREPARATION OF FUSED HETEROAROMATIC PYRROLIDINONES | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-30 | — | — | EP | disclosed |