Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982861 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL25666112 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL7912588 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL2627321 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL20419315 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL10440862 | 0.84 | CHRM2 (0.42) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL24260319 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL24752327 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL17294429 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL24792569 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489236-B1 | PROCESS FOR THE PREPARATION OF FUSED HETEROAROMATIC PYRROLIDINONES | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-30 | — | — | EP | disclosed |