SCHEMBL2248011

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2255059	0.93	EGFR (0.87)	EGFRERBB2ERBB4GAKHDAC2
	SCHEMBL2525148	0.93	EGFR (0.86)	EGFRERBB2ERBB4GAKHDAC2
	SCHEMBL2249040	0.89	EGFR (0.85)	EGFRERBB2ERBB4HDAC2HDAC3
	SCHEMBL2251602	0.88	EGFR (0.87)	EGFRERBB2ERBB4GAKHDAC2
	SCHEMBL20395184	0.87	EGFR (0.85)	EGFRERBB2ERBB4GAKHDAC2
	SCHEMBL2253493	0.86	EGFR (0.68)	EGFRERBB2ERBB4ERBB3DUS2
	SCHEMBL24938253	0.86	EGFR (0.85)	EGFRERBB2ERBB4GAKHDAC2
	SCHEMBL2509718	0.86	EGFR (0.83)	EGFRERBB2ERBB4GAKHDAC2
	SCHEMBL17498589	0.84	EGFR (0.76)	EGFRERBB2ERBB4GAKJAK3
	SCHEMBL17498590	0.84	EGFR (0.76)	EGFRERBB2ERBB4GAKJAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.