Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20614486 | 0.74 | CREBBP (0.52) | BRD4CREBBPEP300CRBN | |
| SCHEMBL357257 | 0.71 | — | — | |
| SCHEMBL25838829 | 0.71 | — | — | |
| SCHEMBL12160740 | 0.71 | — | — | |
| SCHEMBL25838000 | 0.70 | — | — | |
| SCHEMBL7536500 | 0.70 | — | — | |
| SCHEMBL9306449 | 0.70 | — | — | |
| SCHEMBL22504174 | 0.69 | BRD4 (0.34) | BRD4CREBBPEP300CRBNTACR1 | |
| SCHEMBL7430653 | 0.67 | — | — | |
| SCHEMBL14190882 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198379-A1 | TYK2 PSEUDOKINASE LIGANDS | VENTYX BIOSCIENCES, INC. (US) | 2020-10-01 | — | — | WO | disclosed |