⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202089 | 0.89 | — | — | |
| SCHEMBL25125039 | 0.89 | SOS1 (0.32) | — | |
| SCHEMBL24192890 | 0.87 | CYP2D6 (0.41) | — | |
| SCHEMBL25450125 | 0.87 | SOS1 (0.31) | — | |
| SCHEMBL23866789 | 0.85 | — | — | |
| SCHEMBL17173260 | 0.83 | — | — | |
| SCHEMBL12563447 | 0.83 | CYP1A2 (0.33) | — | |
| SCHEMBL15960693 | 0.83 | — | — | |
| SCHEMBL9963379 | 0.81 | SOS1 (0.31) | — | |
| SCHEMBL19194326 | 0.79 | SOS1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007009-A1 | PYRAZOLOPYRIMIDINES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-02-02 | — | — | WO | disclosed |
| US-11332459-B2 | Benzimidazole derivatives and their uses | TEIJIN PHARMA LIMITED (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | AMGEN INC. (US) | 2020-10-01 | — | — | US | disclosed |