Salicylic Acid

Salicylic Acid

SCHEMBL224818

O=C([O-])c1ccccc1O.O=C([O-])c1ccccc1O.[Cu+2]

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.91
HPGD P15428 6/20 0.91
ALDH1A1 P00352 3/20 0.91
SMN1; SMN2 Q16637 3/20 0.58
CA1 P00915 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA2 P00918 1/20 0.58
HMGB1 P09429 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
CA7 P43166 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
CA14 Q9ULX7 1/20 0.58
HSD17B10 Q99714 3/20 0.56
MAPT P10636 3/20 0.56
TSHR P16473 2/20 0.56
GAA P10253 2/20 0.52
MPO P05164 1/20 0.52
HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL31249483 1.00 KDM4E (0.91) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL28064734 0.98 KDM4E (0.86) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL7523064 0.98 KDM4E (0.86) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL28088934 0.98 KDM4E (0.86) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL6249450 0.97 KDM4E (0.95) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL12477386 0.95 KDM4E (0.91) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL10490726 0.95 KDM4E (0.91) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL5142971 0.95 KDM4E (0.91) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL9183232 0.95 KDM4E (0.91) KDM4EHPGDALDH1A1SMN1; SMN2CA1
Salicylic Acid SCHEMBL1932763 0.95 KDM4E (0.91) KDM4EHPGDALDH1A1SMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3154 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3383177-B1 COMPOSITION FOR CROP CARE AND PROTECTION ALPHA BIOPESTICIDES LTD (GB) 2026-04-22 EP claimed
US-20250387415-A1 COMPOSITIONS OF COPPER COMPLEXES University of Lancashire (GB) 2025-12-25 US claimed
US-12454507-B2 Compounds having a fungicidal activity, their agronomic compositions and use thereof for the control of phytopathogenic fungi ISAGRO SPA (IT) 2025-10-28 US claimed
EP-4329704-B1 INITIATOR SYSTEM WITH POLYMERIZABLE THIOUREA COMPONENT, DENTAL COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-10-08 EP claimed
EP-3709994-B1 ORAL ADMINISTRATION FORM COMPRISING AN IRON-COPPER MIXTURE AND ITS USE AS A FOOD SUPPLEMENT PIZETA PHARMA S P A (IT) 2025-09-10 EP claimed
US-20250261644-A1 FUNGICIDAL COMBINATIONS UPL LTD (IN) 2025-08-21 US claimed
EP-4555862-A2 FUNGICIDAL COMBINATIONS UPL Ltd (IN) 2025-05-21 EP claimed
CN-105579048-B Resin biocide composition comprising one or more resins selected from MF, UF, PF, MUF and phenolic resins and one or more soluble copper salts L·A·艾姆斯蒂卡萨拉查 2024-11-26 CN claimed
US-12138323-B2 Initiator system with polymerizable thiourea component, dental composition and use thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-11-12 US claimed
US-12139608-B2 Non-halogenated flame retardant polyamide compositions ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2024-11-12 US claimed
US-4237312-A ACYCLIC CONJUGATED DIOLEFIN ESTRIFIED BY A CARBOXYLIC ACID IN A COPPER OR ANTIMONY COMPOUND CATALYST PHILLIPS PETROLEUM COMPANY (US) 1980-12-02 US claimed
US-4214929-A Liquid monopropellants containing dissolved combustion modifiers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1980-07-29 US claimed
EP-0004570-A1 Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1979-10-17 EP claimed
US-4102953-A Method for making extruded, solventless, composite-modified double base propellant THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-07-25 US claimed
US-4094913-A REACTING 1-BROMO-2,5-DICHLORORENZENE WITH SODIUM HYDROXIDE VELSICOL CHEMICAL CORPORATION (US) 1978-06-13 US claimed
US-4044041-A CARBOXYLIC ACID WITH CONJUGATED DIENE PHILLIPS PETROLEUM COMPANY (US) 1977-08-23 US claimed
US-4021310-A Method for inhibiting the polymerization of acrylic acid or its esters NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JA) 1977-05-03 US claimed
US-4000025-A Incorporating ballistic modifiers in slurry cast double base containing compositions THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1976-12-28 US claimed
US-3994946-A REACTION PRODUCT OF ISOCYANATE WITH LEAD RESORCYLATE AND CUPRIC SALICYLATE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-11-30 US claimed
US-3994757-A PROPELLANTS, NITROCELLULOSE, NITROGLYCERINE, COMPLEX OF ISOCYANATE AND LEAD RESORCYLATE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-11-30 US claimed