⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29130638 | 0.75 | TSHR (0.30) | — | |
| SCHEMBL227499 | 0.74 | — | — | |
| SCHEMBL224948 | 0.73 | — | — | |
| SCHEMBL14931487 | 0.73 | — | — | |
| SCHEMBL224800 | 0.72 | — | — | |
| SCHEMBL224842 | 0.69 | — | — | |
| SCHEMBL5880855 | 0.64 | — | — | |
| SCHEMBL5162681 | 0.60 | — | — | |
| SCHEMBL4632211 | 0.60 | — | — | |
| SCHEMBL5444549 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004166-A1 | ARYLOXYALKYLENE-SUBSTITUTED HYDROXYPHENYLHEXYNOIC ACIDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS A MEDICAMENT | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |