Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 7/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22466044 | 0.81 | ERN1 (0.50) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL29381898 | 0.81 | ERN1 (0.50) | KMT2ARAB9AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL22466009 | 0.76 | KCNQ3 (0.57) | KCNQ3KCNQ2KMT2ARAB9AKDM4E | |
| SCHEMBL29377313 | 0.76 | KCNQ3 (0.57) | KCNQ3KCNQ2KMT2ARAB9AKDM4E | |
| SCHEMBL22485146 | 0.76 | TOP1 (0.43) | KCNQ3KCNQ2 | |
| SCHEMBL29374853 | 0.75 | KCNQ3 (0.53) | KCNQ3KCNQ2RAB9AKDM4EKCNE1 | |
| SCHEMBL22465951 | 0.75 | KCNQ3 (0.53) | KCNQ3KCNQ2RAB9AKDM4EKCNE1 | |
| SCHEMBL29377348 | 0.73 | KCNQ3 (0.71) | KCNQ3KCNQ2RAB9AKDM4EKCNE1 | |
| SCHEMBL22465872 | 0.73 | KCNQ3 (0.71) | KCNQ3KCNQ2RAB9AKDM4EKCNE1 | |
| SCHEMBL22482284 | 0.73 | KCNQ3 (0.70) | KCNQ3KCNQ2RAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198368-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2020-10-01 | — | — | WO | disclosed |