SCHEMBL224865

SCHEMBL224865

[CH]1C=CC2=C1/C=C\C=C/C=C\2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17513045 1.00
SCHEMBL7944187 0.83
SCHEMBL300801 0.78 IDO1 (0.31)
SCHEMBL7941211 0.74
SCHEMBL11272288 0.74
SCHEMBL815828 0.57
SCHEMBL28090128 0.53
SCHEMBL1052145 0.50
SCHEMBL1052146 0.50
SCHEMBL19955877 0.50

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935815-B2 Imidazoyl pyridine compounds and salts thereof EISAI R&D MANAGEMENT CO., LTD. (JP) 2011-05-03 US claimed
EP-3289495-B1 METHOD TO REPRESENT METAL CONTENT IN CRUDE OILS, REACTOR FEEDSTOCKS, AND REACTOR PRODUCTS ASPENTECH CORP (US) 2024-05-29 EP disclosed
EP-3897921-B1 METHOD FOR CO2 ADSORPTION ON METAL ORGANIC FRAMEWORK UNIV MASSEY (NZ) 2024-05-01 EP disclosed
US-11905303-B2 Metal-organic frameworks for gas adsorption MASSEY UNIVERSITY (NZ) 2024-02-20 US disclosed
US-11879019-B2 Dual-enzyme responsive peptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-23 US disclosed
US-11730826-B2 Amphiphilic nanoparticles for delivery of CRISPR based therapy MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-08-22 US disclosed
US-11691949-B2 Quinoline sulfonamide compounds and their use as antibacterial agents OTAGO INNOVATION LIMITED (NZ) 2023-07-04 US disclosed
US-20230190696-A1 Pharmaceutical Formulation for Histone Deacetylase Inhibitors MEDIVIR AB (SE) 2023-06-22 US disclosed
US-20230139366-A1 BRARTEMICIN ANALOGUES VICTORIA LINK LIMITED (NZ) 2023-05-04 US disclosed
US-11607399-B2 Pharmaceutical formulation for histone deacetylase inhibitors MEDIVIR AB 2023-03-21 US disclosed
US-20030220368-A1 Novel piperidine compouds and drugs containing the same EISAI R&D MANAGEMENT CO., LTD. (JP) 2003-11-27 US disclosed
EP-1364952-A1 BICYCLIC NITROGENOUS FUSED-RING COMPOUND Eisai Co., Ltd. (JP) 2003-11-26 EP disclosed
EP-1319659-A1 PYRIDAZINONES AND TRIAZINONES AND MEDICINAL USE THEREOF Eisai Co., Ltd. (JP) 2003-06-18 EP disclosed
WO-2003047577-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES EISAI CO LTD (JP) 2003-06-12 WO disclosed
EP-1308441-A1 2-AMINOPYRIDINE COMPOUNDS AND USE THEREOF AS DRUGS Eisai Co., Ltd. (JP) 2003-05-07 EP disclosed
US-20030078277-A1 Fused heterotricyclic compounds, process for preparing the compounds and drugs containing the same EISAI R&D MANAGEMENT CO., LTD. (JP) 2003-04-24 US disclosed
EP-1300396-A1 1,2-DIHYDROPYRIDINE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF Eisai Co., Ltd. (JP) 2003-04-09 EP disclosed
EP-1254904-A1 NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME Eisai Co., Ltd. (JP) 2002-11-06 EP disclosed
EP-1254895-A1 NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Eisai Co., Ltd. (JP) 2002-11-06 EP disclosed
EP-1238979-A1 FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME Eisai Co., Ltd. (JP) 2002-09-11 EP disclosed