Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20213945 | 0.98 | VHL (0.54) | VHLTAAR1CYP1A2CYP2A6AKT2 | |
| SCHEMBL15110380 | 0.86 | VHL (0.57) | VHLTAAR1CYP1A2CYP2A6AKT2 | |
| SCHEMBL25006603 | 0.85 | VHL (0.56) | VHLCYP1A2KDM4EALDH1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL21070735 | 0.85 | VHL (0.56) | VHLTAAR1CYP1A2CYP2A6AKT2 | |
| Hydrochloric Acid SCHEMBL26909801 | 0.85 | VHL (0.56) | VHLTAAR1CYP1A2CYP2A6AKT2 | |
| SCHEMBL19598702 | 0.83 | VHL (0.58) | VHLCYP1A2KDM4EALDH1A1CYP2C19 | |
| SCHEMBL16276343 | 0.81 | VHL (0.59) | VHLCYP1A2KDM4EALDH1A1CYP2C19 | |
| SCHEMBL22481765 | 0.81 | HRH3 (0.55) | VHLTAAR1HTR1A | |
| SCHEMBL25592938 | 0.81 | VHL (0.56) | VHLCYP1A2KDM4EALDH1A1CYP2C19 | |
| SCHEMBL22130274 | 0.80 | VHL (0.50) | VHLCYP1A2KDM4EALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994300-A | Protein degradation targeting chimeric and application thereof | 沈阳药科大学 | 2024-11-22 | — | — | CN | disclosed |
| WO-2020198055-A1 | ALLOSTERIC BCR-ABL PROTEOLYSIS TARGETING CHIMERIC COMPOUNDS | YALE UNIVERSITY (US) | 2020-10-01 | — | — | WO | disclosed |