SCHEMBL22487983

SCHEMBL22487983

CC(F)(F)C1CNCCO1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 12/20 0.37
HTR1A P08908 1/20 0.36
SSTR4 P31391 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28684483 0.98 SLC6A2 (0.36) SLC6A2HTR1ASSTR4
SCHEMBL1287870 0.87 SLC6A2 (0.37) SLC6A2HTR1ASSTR4
SCHEMBL22265190 0.83 SLC6A2 (0.36) SLC6A2HTR1ASSTR4
SCHEMBL12504907 0.82 SLC6A2 (0.39) SLC6A2HTR1ASSTR4
SCHEMBL19366757 0.82 SLC6A2 (0.39) SLC6A2HTR1ASSTR4
SCHEMBL17340716 0.82 SLC6A2 (0.39) SLC6A2HTR1A
SCHEMBL17409968 0.82 SLC6A2 (0.39) SLC6A2HTR1ASSTR4
SCHEMBL627761 0.82 SLC6A2 (0.39) SLC6A2HTR1ASSTR4
SCHEMBL12275915 0.82 SLC6A2 (0.39) SLC6A2HTR1A
SCHEMBL17340694 0.82 SLC6A2 (0.39) SLC6A2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 US disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 US disclosed
WO-2020198058-A1 INHIBITORS OF RAF KINASES KINNATE BIOPHARMA INC. (US) 2020-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF TYK2, JAK1, JAK3 SLC6A2 4424/4885HTR1A 2632/4885SSTR4 3879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.