Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.59 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662273 | 0.87 | PIK3CD (0.73) | CYP2A6NPC1RAB9APIK3CDCYP1A2 | |
| SCHEMBL18770664 | 0.86 | NPC1 (0.54) | CYP2A6NPC1RAB9APIK3CDKCNQ3 | |
| SCHEMBL1742300 | 0.83 | PIK3CD (0.61) | CYP2A6NPC1RAB9APIK3CDKCNQ3 | |
| SCHEMBL21677813 | 0.83 | NPC1 (0.56) | CYP2A6NPC1RAB9APIK3CDKCNQ3 | |
| SCHEMBL1742451 | 0.80 | CYP2A6 (1.00) | CYP2A6NPC1RAB9APIK3CDSMN1; SMN2 | |
| SCHEMBL28822240 | 0.80 | SMO (0.51) | CYP2A6NPC1RAB9APIK3CDKCNQ3 | |
| SCHEMBL4729780 | 0.79 | PIK3CD (0.69) | CYP2A6NPC1RAB9APIK3CDSMN1; SMN2 | |
| SCHEMBL1742549 | 0.79 | CYP2A6 (0.64) | CYP2A6NPC1RAB9APIK3CDSMN1; SMN2 | |
| SCHEMBL11160404 | 0.79 | PIK3CD (0.57) | CYP2A6NPC1RAB9APIK3CDKCNQ3 | |
| SCHEMBL11167793 | 0.79 | PIK3CD (0.57) | CYP2A6NPC1RAB9APIK3CDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117926286-A | Synthesis method of 1-chlorobenzo [4,5] thieno [2,3-c ] pyridine | 中钢天源股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-103819395-B | A kind of method of preparing the iodo-5-phenylpyridine of 2- | CHINA SYNCHEM TECHNOLOGY CO., LTD. (CN) | 2016-05-25 | — | — | CN | claimed |
| CN-104755477-A | 2-aminopyridine compounds | MERCK PATENT GMBH | 2015-07-01 | — | — | CN | claimed |
| CN-102712589-B | Aryl-pyridine derivatives as aldosterone synthase inhibitors | NOVARTIS AG | 2015-05-13 | — | — | CN | claimed |
| CN-102171202-B | Pyridine and pyrimidine based compounds as WNT signaling pathway inhibitors for the treatment of cancer | CANCER REC TECH LTD | 2015-01-07 | — | — | CN | claimed |
| CN-103819395-A | Method for preparing 2-iodine-5-phenylpyridine | CHINA SYNCHEM TECHNOLOGY CO LTD | 2014-05-28 | — | — | CN | claimed |
| EP-1924558-B1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2010-01-13 | — | — | EP | claimed |
| EP-1924558-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-05-28 | — | — | EP | claimed |
| WO-2007032016-A1 | AN ANTIMALARIAL BAYLIS-HILLMAN ADDUCTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-03-22 | — | — | WO | claimed |
| CN-117926286-B | Synthesis method of 1-chlorobenzo [4,5] thieno [2,3-c ] pyridine | 中钢天源股份有限公司 | 2025-10-17 | — | — | CN | disclosed |
| CN-118047654-A | Process for preparing aryl halides starting from aromatic amines | 黑龙江立科新材料有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117926286-A | Synthesis method of 1-chlorobenzo [4,5] thieno [2,3-c ] pyridine | 中钢天源股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117926286-A | Synthesis method of 1-chlorobenzo [4,5] thieno [2,3-c ] pyridine | 中钢天源股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-111527094-B | Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device | 学校法人关西学院 | 2024-03-26 | — | — | CN | disclosed |
| US-4242515-A | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo-[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| EP-0017438-A1 | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo(4,3-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4209626-A | Substituted 6-phenyl-1,2,4-triazolo[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |
| US-4192944-A | ANTIANAPHYLACTIC | BRISTOL-MYERS COMPANY (US) | 1980-03-11 | — | — | US | disclosed |
| US-4122274-A | ANTIALLERGY | BRISTOL-MYERS COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4078063-A | ANOREXIC AGENTS | MERCK & CO., INC. (US) | 1978-03-07 | — | — | US | disclosed |