SCHEMBL22489537

SCHEMBL22489537

CC1CN(c2ccc(Cl)nn2)CCN1C(=O)Cc1ccc(N(C)C)cc1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PANK3 Q9H999 19/20 0.75
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22489205 1.00 PANK3 (0.75) PANK3HPGD
SCHEMBL22489209 1.00 PANK3 (0.75) PANK3HPGD
SCHEMBL22609121 0.86 PANK3 (1.00) PANK3HPGD
SCHEMBL22609120 0.86 PANK3 (1.00) PANK3HPGD
SCHEMBL22489203 0.83 PANK3 (1.00) PANK3
SCHEMBL22489204 0.80 PANK3 (0.70) PANK3
SCHEMBL22489208 0.80 PANK3 (0.70) PANK3
SCHEMBL22489456 0.80 PANK3 (0.70) PANK3
SCHEMBL23040152 0.79 PANK3 (1.00) PANK3
SCHEMBL22920471 0.79 PANK3 (1.00) PANK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020198526-A2 SMALL MOLECULE MODULATORS OF PANK ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2020-10-01 WO disclosed