Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | FRK | P42685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22490365 | 0.82 | MAPK14 (0.52) | MAPK14ALDH1A1SMN1; SMN2HPGDLCK | |
| SCHEMBL22490204 | 0.81 | SMN1; SMN2 (0.50) | MAPK14ALDH1A1SMN1; SMN2HPGDLCK | |
| SCHEMBL10043911 | 0.77 | MAPK14 (0.62) | MAPK14ALDH1A1SMN1; SMN2HPGDLCK | |
| SCHEMBL22468550 | 0.76 | SMN1; SMN2 (0.58) | MAPK14ALDH1A1SMN1; SMN2HPGDLCK | |
| SCHEMBL5070509 | 0.76 | SMN1; SMN2 (0.58) | MAPK14ALDH1A1SMN1; SMN2HPGDLCK | |
| SCHEMBL29477055 | 0.76 | SMN1; SMN2 (0.58) | MAPK14ALDH1A1SMN1; SMN2HPGDLCK | |
| SCHEMBL1233477 | 0.76 | SMN1; SMN2 (0.58) | MAPK14ALDH1A1SMN1; SMN2HPGDLCK | |
| SCHEMBL2074433 | 0.76 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL1406122 | 0.75 | MAPK14 (0.51) | MAPK14ALDH1A1HPGDLCKMEN1 | |
| SCHEMBL29476868 | 0.74 | MAPK14 (0.45) | MAPK14ALDH1A1HPGDLCKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198053-A1 | 2-OXO-2,3-DIHYDRO-1H-IMIDAZO[4,5-B]PYRIDIN-6-YL)-4-METHYLBENZAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS RIPK2 INHIBITORS FOR TREATING E.G. AUTOIMMUNE DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-10-01 | — | — | WO | disclosed |