Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | SQLE | Q14534 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22490635 | 1.00 | KDM1A (0.58) | KDM1APTPN1SQLEKMT2ANR1I2 | |
| SCHEMBL2835870 | 0.87 | KDM1A (0.58) | KDM1APTPN1SQLEKMT2ANR1I2 | |
| SCHEMBL2579524 | 0.84 | KDM1A (0.71) | KDM1APTPN1SQLEKMT2AMAPT | |
| SCHEMBL2832173 | 0.83 | NR1I2 (0.61) | KDM1APTPN1SQLEKMT2ANR1I2 | |
| SCHEMBL10741827 | 0.83 | KDM1A (0.61) | KDM1APTPN1SQLENR1I2LMNA | |
| SCHEMBL10741830 | 0.83 | KDM1A (0.61) | KDM1APTPN1SQLENR1I2LMNA | |
| SCHEMBL6907667 | 0.81 | KDM1A (0.59) | KDM1APTPN1SQLEKMT2AMAPT | |
| SCHEMBL8735440 | 0.81 | KDM1A (0.64) | KDM1APTPN1SQLEKMT2AALDH1A1 | |
| SCHEMBL6907669 | 0.81 | KDM1A (0.59) | KDM1APTPN1SQLEKMT2AMAPT | |
| SCHEMBL29663830 | 0.81 | KDM1A (0.64) | KDM1APTPN1SQLEKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286308-B1 | ENZYMES AND APPLICATIONS THEREOF | GIVAUDAN SA (CH) | 2020-10-07 | — | — | EP | disclosed |