Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.94 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21145607 | 0.97 | KLKB1 (1.00) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| Hydrochloric Acid SCHEMBL22528249 | 0.96 | KLKB1 (0.98) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| Sulfuric Acid SCHEMBL22528251 | 0.94 | KLKB1 (0.94) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| Sebetralstat SCHEMBL29619273 | 0.86 | KLKB1 (1.00) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| Sebetralstat SCHEMBL17785421 | 0.86 | KLKB1 (1.00) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL21145545 | 0.86 | KLKB1 (1.00) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| Sebetralstat SCHEMBL28770013 | 0.86 | KLKB1 (0.98) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| Sebetralstat SCHEMBL22495449 | 0.86 | KLKB1 (0.98) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL21145597 | 0.85 | KLKB1 (1.00) | KLKB1CYP3A4CYP2C8CYP2C9 | |
| Sebetralstat SCHEMBL22495443 | 0.84 | KLKB1 (0.95) | KLKB1CYP3A4CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717468-A1 | SOLID FORMS OF A PLASMA KALLIKREIN INHIBITOR AND SALTS THEREOF | Kalvista Pharmaceuticals Limited (GB) | 2020-10-07 | — | — | EP | disclosed |