Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26247554 | 0.93 | MAPT (0.51) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL22492511 | 0.83 | MAPT (0.44) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL22492626 | 0.80 | MAPT (0.52) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL26247537 | 0.79 | MAPT (0.53) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL22492413 | 0.79 | MAPT (0.45) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL17837048 | 0.77 | MAPT (0.49) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL22492463 | 0.76 | MAPT (0.43) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL22492433 | 0.76 | CA12 (0.53) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL22492488 | 0.76 | MAPT (0.43) | MAPTKMT2ALMNAMEN1NPSR1 | |
| SCHEMBL26247578 | 0.75 | MAPT (0.51) | MAPTKMT2ALMNAMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717453-A2 | CREATINE PRODRUGS, COMPOSITIONS AND METHODS OF USE THEREOF | Ultragenyx Pharmaceutical Inc. (US) | 2020-10-07 | — | — | EP | disclosed |
| CN-111417620-A | Creatine prodrugs, compositions thereof, and methods of use | 奥特吉尼克斯制药公司 | 2020-07-14 | — | — | CN | disclosed |