⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808156 | 0.75 | — | — | |
| SCHEMBL2315679 | 0.75 | — | — | |
| SCHEMBL31358499 | 0.71 | — | — | |
| SCHEMBL1516762 | 0.71 | — | — | |
| SCHEMBL31555009 | 0.71 | — | — | |
| SCHEMBL25261269 | 0.71 | — | — | |
| SCHEMBL8223090 | 0.71 | — | — | |
| SCHEMBL342510 | 0.71 | — | — | |
| SCHEMBL4485178 | 0.71 | — | — | |
| SCHEMBL565906 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874363-B | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2024-11-12 | — | — | CN | disclosed |
| US-20240124453-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2024-04-18 | — | — | US | disclosed |
| US-11884664-B2 | Protein tyrosine phosphatase inhibitors | ARRAY BIOPHARMA INC. (US) | 2024-01-30 | — | — | US | disclosed |
| CN-114262293-B | Preparation method of 2-amino-3-bromopyridine | 上海有吉医药化工有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-11634417-B2 | Protein tyrosine phosphatase inhibitors | ARRAY BIOPHARMA INC. (US) | 2023-04-25 | — | — | US | disclosed |
| CN-114426516-B | Preparation method of 2-amino-3-bromopyridine | 安徽有吉医药科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-20220251083-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2022-08-11 | — | — | US | disclosed |
| CN-114426516-A | Preparation method of 2-amino-3-bromopyridine | 安徽有吉医药科技有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-114262293-A | Preparation method of 2-amino-3-bromopyridine | 安徽有吉医药科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-3947367-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | Array Biopharma, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113874363-A | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2021-12-31 | — | — | CN | disclosed |
| US-20200317665-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2020-10-08 | — | — | US | disclosed |
| WO-2020201991-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2020-10-08 | — | — | WO | disclosed |