SCHEMBL22493939

SCHEMBL22493939

OC(COCC1CO1)COc1ccc(C2(c3ccc(OCC(O)COCC4CO4)cc3)Cc3ccccc3C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
NPY1R P25929 1/20 0.37
PRMT5 O14744 3/20 0.37
WDR77 Q9BQA1 3/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
HPGD P15428 3/20 0.36
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 4/20 0.34
TP53 P04637 3/20 0.34
TSHR P16473 3/20 0.34
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HIF1A Q16665 2/20 0.34
HTT P42858 2/20 0.34
PPARG P37231 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12009487 0.93 TDP1 (0.49) TDP1NPY1RPRMT5WDR77MEN1
SCHEMBL12009483 0.86 TDP1 (0.45) TDP1NPY1RPRMT5WDR77MEN1
SCHEMBL12009496 0.85 TDP1 (0.44) TDP1NPY1RPRMT5WDR77MEN1
SCHEMBL12009494 0.84 TDP1 (0.43) TDP1NPY1RPRMT5WDR77MEN1
SCHEMBL12009558 0.84 TDP1 (0.47) TDP1NPY1RPRMT5WDR77MEN1
SCHEMBL20492221 0.82 TDP1 (0.60) TDP1MEN1KMT2AHPGDCYP1A2
SCHEMBL23589323 0.82 TDP1 (0.60) TDP1MEN1KMT2ACYP3A4CYP2D6
SCHEMBL20492279 0.82 TDP1 (0.45) TDP1MEN1KMT2AHPGDCYP1A2
SCHEMBL22493949 0.81 TDP1 (0.36) TDP1NPY1RPRMT5WDR77MEN1
SCHEMBL12009493 0.81 TDP1 (0.47) TDP1NPY1RPRMT5WDR77MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200319549-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, ELEMENT HAVING CURED FILM, ORGANIC EL DISPLAY, AND METHOD FOR MANUFACTURING ORGANIC EL DISPLAY TORAY INDUSTRIES, INC. (JP) 2020-10-08 US disclosed
CN-111164512-A Photosensitive resin composition, cured film, element provided with cured film, organic EL display, and method for manufacturing organic EL display 东丽株式会社 2020-05-15 CN disclosed