Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.55 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 4/20 | 0.51 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.44 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.44 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.44 |
| ▸ | DHPS | P49366 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196046 | 0.86 | ASH1L (0.65) | PIK3CDASH1LHPGDSPIK3CBPIK3CG | |
| SCHEMBL2947880 | 0.86 | PIK3CD (0.57) | PIK3CDASH1LHPGDSPIK3CBPIK3CG | |
| SCHEMBL2948502 | 0.84 | PIK3CD (0.51) | PIK3CDASH1LHPGDSPIK3CBPIK3CG | |
| SCHEMBL27698578 | 0.79 | NR4A2 (0.58) | ASH1LMAPTSMN1; SMN2ABL1SGK1 | |
| SCHEMBL10945814 | 0.79 | PIK3CD (0.75) | PIK3CDASH1LHPGDSPIK3CBPIK3CG | |
| SCHEMBL13115632 | 0.78 | PIK3CD (0.64) | PIK3CDASH1LHPGDSPIK3CBPIK3CG | |
| SCHEMBL27504678 | 0.78 | PIK3CD (0.64) | PIK3CDASH1LHPGDSPIK3CBPIK3CG | |
| SCHEMBL27725234 | 0.76 | PIK3CD (0.66) | PIK3CDASH1LHPGDSPIK3CBPIK3CG | |
| SCHEMBL2193011 | 0.76 | PIK3CD (0.70) | PIK3CDASH1LHPGDSPIK3CBPIK3CG | |
| SCHEMBL29712113 | 0.76 | PIK3CD (0.70) | PIK3CDASH1LHPGDSPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198478-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2020-10-01 | — | — | WO | disclosed |