Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of N-Benzylmethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.90 |
| ▸ | MAPT | P10636 | 2/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.90 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Benzylmethylamine SCHEMBL2271 | 0.97 | — | — | |
| SCHEMBL24334039 | 0.97 | CYP3A4 (0.94) | CYP3A4MAPTKDM4EATMTAAR1 | |
| N-Benzylmethylamine SCHEMBL4609847 | 0.97 | CYP3A4 (0.94) | CYP3A4MAPTKDM4EATMTAAR1 | |
| N-Benzylmethylamine SCHEMBL11696446 | 0.97 | CYP3A4 (0.94) | CYP3A4MAPTKDM4EATMTAAR1 | |
| N-Benzylmethylamine SCHEMBL8083805 | 0.94 | — | — | |
| N-Benzylmethylamine SCHEMBL31281074 | 0.94 | CYP3A4 (0.90) | CYP3A4MAPTKDM4EATMTAAR1 | |
| N-Benzylmethylamine SCHEMBL837568 | 0.94 | CYP3A4 (0.90) | CYP3A4MAPTKDM4EATMTAAR1 | |
| N-Benzylmethylamine SCHEMBL9346326 | 0.94 | CYP3A4 (0.90) | CYP3A4MAPTKDM4EATMTAAR1 | |
| N-Benzylmethylamine SCHEMBL237384 | 0.94 | MAPT (1.00) | CYP3A4MAPTKDM4EATMTAAR1 | |
| N-Benzylmethylamine SCHEMBL27370226 | 0.94 | MAPT (1.00) | CYP3A4MAPTKDM4EATMTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116145324-A | Dark blue light circularly polarized light-emitting film and preparation method and application thereof | 温州大学 | 2023-05-23 | — | — | CN | claimed |
| CN-110387257-A | Suitable for clear tank oil demetalization metal remover and combinations thereof and clear tank oil treatment process | 中国石油化工股份有限公司 | 2019-10-29 | — | — | CN | claimed |
| CN-110066646-A | A kind of oil base drilling fluid compound organic clay and its preparation method | 中国地质大学（北京） | 2019-07-30 | — | — | CN | claimed |
| CN-105153485-B | A kind of nano modification glue gel resin and preparation method thereof | 澄迈诚善农业有限公司 | 2019-06-25 | — | — | CN | claimed |
| CN-109674679-A | A kind of skin barrier maintenance biomembrane and preparation method thereof | 贝德氏（上海）健康科技股份有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109568216-A | A kind of skin barrier maintenance Mu Lu and preparation method thereof | 贝德氏（上海）健康科技股份有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-108812670-A | Floor anti-mould and moth-proof agent composition and preparation method thereof | 安吉汉洲生物科技有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-108676289-A | A kind of antifouling anti-corrosion sewage disposal special PVC pipeline and preparation method thereof | 安庆市洁达塑业有限公司 | 2018-10-19 | — | — | CN | claimed |
| CN-106380554-B | A kind of preparation method of esters viscosity reduction type polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-105532660-B | A kind of compound disinfectant and its application | 成都科宏达科技有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-108084440-A | A kind of high stable cationoid hydroxyl silicon oil emulsion and preparation method | 上海应用技术大学 | 2018-05-29 | — | — | CN | claimed |
| CN-104178099-B | A kind of temperature-resistant and anti-salt type nanoemulsions and its preparation method and application | 中国石油化工股份有限公司 | 2017-11-17 | — | — | CN | claimed |
| CN-107155367-A | Aqueous and half aqueous cleaning agent of post-etch residues is removed using tungsten and cobalt compatibility | 恩特格里斯公司 | 2017-09-12 | — | — | CN | claimed |
| CN-107129647-A | A kind of fire-retardant degradable environmental protection macromolecule foamed material and preparation method thereof | 广西南宁桂尔创环保科技有限公司 | 2017-09-05 | — | — | CN | claimed |
| CN-107094777-A | Composition for preventing and treating agricultural bacterial diseases and killing snail | 中国农业科学院植物保护研究所 | 2017-08-29 | — | — | CN | claimed |
| CN-106380554-A | Preparation method of ester type viscosity reduction type polycarboxylate superplasticizer | 科之杰新材料集团有限公司 | 2017-02-08 | — | — | CN | claimed |
| CN-106047525-A | Cleaning treating agent for smart home | 王璐 | 2016-10-26 | — | — | CN | claimed |
| EP-0900214-A1 | PROCESS FOR PREPARATION OF PYRIMIDINE DERIVATIVES | Yuhan Corporation (KR) | 1999-03-10 | — | — | EP | claimed |
| WO-1998018784-A1 | PROCESS FOR PREPARATION OF PYRIMIDINE DERIVATIVES | YUHAN CORPORATION (KR) | 1998-05-07 | — | — | WO | claimed |
| WO-1997042186-A1 | PROCESS FOR PREPARATION OF PYRIMIDINE DERIVATIVES | YUHAN CORPORATION (KR) | 1997-11-13 | — | — | WO | claimed |