Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.88 |
| ▸ | IGF1R | P08069 | 1/20 | 0.88 |
| ▸ | MLNR | O43193 | 1/20 | 0.77 |
| ▸ | KDM1A | O60341 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.77 |
| ▸ | INSR | P06213 | 1/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | HTR1A | P08908 | 1/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.77 |
| ▸ | DRD2 | P14416 | 1/20 | 0.77 |
| ▸ | NQO2 | P16083 | 1/20 | 0.77 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.77 |
| ▸ | DRD1 | P21728 | 1/20 | 0.77 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.77 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.77 |
| ▸ | HTR2A | P28223 | 1/20 | 0.77 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.77 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860673 | 0.94 | EGFR (1.00) | EGFRIGF1RMLNRKDM1AABCB11 | |
| SCHEMBL30379658 | 0.94 | EGFR (1.00) | EGFRIGF1RMLNRKDM1AABCB11 | |
| SCHEMBL14661086 | 0.94 | EGFR (1.00) | EGFRIGF1RMLNRKDM1AABCB11 | |
| Hydrochloric Acid SCHEMBL30735819 | 0.93 | EGFR (0.99) | EGFRIGF1RMLNRKDM1AABCB11 | |
| Hydrochloric Acid SCHEMBL30735856 | 0.93 | EGFR (0.99) | EGFRIGF1RMLNRKDM1AABCB11 | |
| Hydrochloric Acid SCHEMBL26637892 | 0.93 | EGFR (0.99) | EGFRIGF1RMLNRKDM1AABCB11 | |
| SCHEMBL22509190 | 0.93 | EGFR (0.88) | EGFRIGF1RMLNRKDM1AABCB11 | |
| SCHEMBL22509155 | 0.91 | EGFR (0.77) | EGFRIGF1RMLNRKDM1AABCB11 | |
| SCHEMBL22509192 | 0.91 | EGFR (0.85) | EGFRIGF1RMLNRKDM1AABCB11 | |
| SCHEMBL30682157 | 0.91 | EGFR (0.95) | EGFRIGF1RMLNRKDM1AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258344-B2 | Azaaromatic amide derivatives for the treatment of cancer | SHENZHEN FORWARD PHARMACEUTICALS CO., LTD. (CN) | 2025-03-25 | — | — | US | disclosed |
| US-20220177473-A1 | AZAAROMATIC AMIDE DERIVATIVES FOR THE TREATMENT OF CANCER | SHENZHEN FORWARD PHARMACEUTICALS CO., LTD. (CN) | 2022-06-09 | — | — | US | disclosed |
| US-20220177473-A1 | AZAAROMATIC AMIDE DERIVATIVES FOR THE TREATMENT OF CANCER | SHENZHEN FORWARD PHARMACEUTICALS CO., LTD. (CN) | 2022-06-09 | — | — | US | disclosed |
| EP-3950686-A1 | N-HETEROAROMATIC AMIDE DERIVATIVES FOR TREATMENT OF CANCER | Shenzhen Forward Pharmaceuticals Co., Ltd. (CN) | 2022-02-09 | — | — | EP | disclosed |
| CN-113727982-A | Azaaromatic cyclic amide derivatives for the treatment of cancer | 深圳福沃药业有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-111747931-A | Azaaromatic cyclic amide derivatives for the treatment of cancer | 深圳福沃药业有限公司 | 2020-10-09 | — | — | CN | disclosed |
| WO-2020200158-A1 | N-HETEROAROMATIC AMIDE DERIVATIVES FOR TREATMENT OF CANCER | 深圳福沃药业有限公司 | 2020-10-08 | — | — | WO | disclosed |
| WO-2020200158-A1 | N-HETEROAROMATIC AMIDE DERIVATIVES FOR TREATMENT OF CANCER | 深圳福沃药业有限公司 | 2020-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177473-A1 | AZAAROMATIC AMIDE DERIVATIVES FOR THE TREATMENT OF CANCER | ERBB4, EGFR, ERBB2 | EGFR 2/4885IGF1R 47/4885MLNR 487/4885 |
| US-12258344-B2 | Azaaromatic amide derivatives for the treatment of cancer | ERBB4, EGFR, ERBB2 | EGFR 2/4885IGF1R 47/4885MLNR 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.