SCHEMBL22497787

SCHEMBL22497787

CCCCCOC(=O)c1cccc(OC)c1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
NPSR1 Q6W5P4 1/20 0.57
MAPT P10636 2/20 0.55
GAA P10253 1/20 0.55
LMNA P02545 2/20 0.55
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
TSHR P16473 2/20 0.54
TP53 P04637 1/20 0.54
CYP3A4 P08684 1/20 0.54
MAPK1 P28482 1/20 0.54
SMPD1 P17405 3/20 0.53
ALDH1A1 P00352 1/20 0.53
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8457667 0.99 MEN1 (0.64) MEN1KMT2ASMN1; SMN2NPSR1MAPT
SCHEMBL27924933 0.99 MEN1 (0.64) MEN1KMT2ASMN1; SMN2NPSR1MAPT
SCHEMBL8458602 0.99 MEN1 (0.64) MEN1KMT2ASMN1; SMN2NPSR1MAPT
SCHEMBL22498355 0.99 MEN1 (0.64) MEN1KMT2ASMN1; SMN2NPSR1MAPT
Methane SCHEMBL29016050 0.99 MEN1 (0.64) MEN1KMT2ASMN1; SMN2NPSR1MAPT
SCHEMBL11245249 0.99 MEN1 (0.64) MEN1KMT2ASMN1; SMN2NPSR1MAPT
SCHEMBL4450097 0.95 SMN1; SMN2 (0.67) MEN1KMT2ASMN1; SMN2NPSR1MAPT
SCHEMBL17961066 0.90 SMPD1 (0.66) KMT2ALMNATSHRTP53CYP3A4
SCHEMBL11505600 0.89 SMN1; SMN2 (0.70) MEN1KMT2ASMN1; SMN2NPSR1MAPT
SCHEMBL18668820 0.88 MEN1 (0.61) MEN1KMT2ASMN1; SMN2NPSR1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3946240-B1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO KGAA (DE) 2025-10-15 EP claimed
US-20220211602-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-07-07 US claimed
EP-3946240-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-02-09 EP claimed
CN-113677319-A Increasing the stability of agents for treating keratin materials 汉高股份有限及两合公司 2021-11-19 CN claimed
WO-2020200545-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2020-10-08 WO claimed
US-20220211602-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-07-07 US disclosed
EP-3946240-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-02-09 EP disclosed
CN-113677319-A Increasing the stability of agents for treating keratin materials 汉高股份有限及两合公司 2021-11-19 CN disclosed
WO-2020200545-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2020-10-08 WO disclosed
WO-2020200545-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2020-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211602-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL KRT18, CCNA1, CCNA2 MEN1 535/4885KMT2A 519/4885SMN1; SMN2 2729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.