Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26080844 | 0.83 | KDM4E (0.42) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL18133632 | 0.80 | CSNK2A1 (0.33) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL21319559 | 0.78 | MAPT (0.40) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL18875993 | 0.76 | MAPT (0.33) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL20126952 | 0.76 | KDM4E (0.39) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL131396 | 0.76 | KDM4E (0.43) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL29594290 | 0.76 | KDM4E (0.43) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL20146542 | 0.75 | KDM4E (0.36) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL22504304 | 0.75 | MAPT (0.45) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL22504301 | 0.74 | MAPT (0.36) | MAPTKDM4ETSHRCYP2A6CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020203594-A1 | FLUORENE DERIVATIVE AND USE THEREOF | 日産化学株式会社 | 2020-10-08 | — | — | WO | disclosed |