SCHEMBL22504307

SCHEMBL22504307

Cc1csc2c1ccc1ccsc12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.32
KCNA3 P22001 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18133645 0.89 CYP2A6 (0.31) CYP2A6
SCHEMBL4420462 0.82 CYP2A6 (0.41) CYP2A6KCNA3
SCHEMBL4423927 0.76 CYP2A6 (0.32) CYP2A6
SCHEMBL4429340 0.76 CYP2A6 (0.32) CYP2A6
SCHEMBL22504301 0.75 MAPT (0.36) CYP2A6
SCHEMBL793638 0.75 CYP2A6 (0.46) CYP2A6
SCHEMBL18195312 0.74 CYP2A6 (0.36) CYP2A6KCNA3
SCHEMBL18133636 0.73 CYP2A6 (0.39) CYP2A6KCNA3
SCHEMBL12279370 0.73 CYP2A6 (0.39) CYP2A6KCNA3
SCHEMBL2368459 0.73 CYP2A6 (0.41) CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020203594-A1 FLUORENE DERIVATIVE AND USE THEREOF 日産化学株式会社 2020-10-08 WO disclosed