Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22498300 | 0.93 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL30679715 | 0.93 | PIK3CD (0.40) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL24494696 | 0.91 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL22504968 | 0.84 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL29641515 | 0.84 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL24494695 | 0.84 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL16783540 | 0.81 | PIK3CD (0.46) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL21337751 | 0.81 | PIK3CD (0.38) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL16783796 | 0.80 | PIK3CD (0.42) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA | |
| SCHEMBL24494700 | 0.78 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3R1CSNK1EPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947384-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2023-11-01 | — | — | EP | disclosed |
| WO-2020200918-A1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2020-10-08 | — | — | WO | disclosed |