Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.57 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.57 |
| ▸ | KIT | P10721 | 4/20 | 0.57 |
| ▸ | RET | P07949 | 4/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.57 |
| ▸ | FLT1 | P17948 | 3/20 | 0.57 |
| ▸ | FLT4 | P35916 | 3/20 | 0.57 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.57 |
| ▸ | ABL1 | P00519 | 3/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.57 |
| ▸ | STK10 | O94804 | 2/20 | 0.57 |
| ▸ | BCR | P11274 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.57 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.57 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.57 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.57 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.57 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22505603 | 0.92 | KDR (0.68) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22535129 | 0.92 | KDR (0.55) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22505693 | 0.91 | KDR (0.56) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22505607 | 0.88 | KDR (0.50) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22505653 | 0.87 | PDGFRA (0.52) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22505591 | 0.87 | PDGFRA (0.53) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22505717 | 0.85 | KDR (0.58) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22505568 | 0.85 | PDGFRA (0.48) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22505601 | 0.85 | KDR (0.58) | KDRPDGFRAAURKBKITRET | |
| SCHEMBL22505615 | 0.84 | KDR (0.56) | KDRPDGFRAAURKBKITRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800741-B2 | Quinoline compound, preparation method and medical use therefor | ANCUREALL PHARMACEUTICAL (SHANGHAI) CO., LTD. (CN) | 2020-10-13 | — | — | US | disclosed |
| US-10800741-B2 | Quinoline compound, preparation method and medical use therefor | ANCUREALL PHARMACEUTICAL (SHANGHAI) CO., LTD. (CN) | 2020-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800741-B2 | Quinoline compound, preparation method and medical use therefor | WEE2, WEE1, HASPIN | KDR 2448/4885PDGFRA 2993/4885AURKB 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.