SCHEMBL22507366

SCHEMBL22507366

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-n4c5ccccc5c5ccccc54)cc3)c3ccc(-n4c5ccccc5c5ccccc54)cc3)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PDK2 Q15119 3/20 0.34
PGR P06401 4/20 0.32
ALK Q9UM73 2/20 0.31
MLNR O43193 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRB1 P08588 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
CHRM3 P20309 1/20 0.30
DRD1 P21728 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17722209 1.00 KDM4E (0.39) KDM4EATML3MBTL1PDK2PGR
SCHEMBL401420 0.97 KDM4E (0.41) KDM4EATML3MBTL1PDK2PGR
SCHEMBL31493379 0.97 KDM4E (0.41) KDM4EATML3MBTL1PDK2PGR
SCHEMBL22952581 0.96 KDM4E (0.36) KDM4EATML3MBTL1PDK2HDAC4
SCHEMBL20707479 0.96 KDM4E (0.36) KDM4EATML3MBTL1PDK2HDAC4
SCHEMBL24948652 0.96 KDM4E (0.36) KDM4EATML3MBTL1PDK2
SCHEMBL21010906 0.96 KDM4E (0.36) KDM4EATML3MBTL1PDK2HDAC4
SCHEMBL13620224 0.96 KDM4E (0.36) KDM4EATML3MBTL1PDK2HDAC4
SCHEMBL16436443 0.96 KDM4E (0.36) KDM4EATML3MBTL1PDK2HDAC4
SCHEMBL21128953 0.95 KDM4E (0.36) KDM4EATML3MBTL1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020199997-A1 SUBSTITUTED 1,3,5-TRIAZINE COMPOUND, COMPOSITION AND APPLICATION THEREOF 吉林省元合电子材料有限公司 2020-10-08 WO disclosed
WO-2020199996-A1 SUBSTITUTED 1,3,5-TRIAZINE COMPOUND, COMPOSITION AND APPLICATION THEREOF 吉林省元合电子材料有限公司 2020-10-08 WO disclosed
WO-2020199998-A1 1,3,5-TRIAZINE COMPOUND AND COMPOSITION, AND APPLICATION THEREOF 吉林省元合电子材料有限公司 2020-10-08 WO disclosed