Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 8/20 | 0.79 |
| ▸ | CHEK1 | O14757 | 12/20 | 0.75 |
| ▸ | FLT3 | P36888 | 9/20 | 0.75 |
| ▸ | KIT | P10721 | 2/20 | 0.61 |
| ▸ | STK17B | O94768 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917526 | 0.88 | STK17A (0.79) | STK17ACHEK1FLT3KITSTK17B | |
| SCHEMBL1917543 | 0.88 | STK17A (1.00) | STK17ACHEK1FLT3STK17B | |
| SCHEMBL28380266 | 0.85 | CHEK1 (0.77) | STK17ACHEK1FLT3KITSTK17B | |
| SCHEMBL1916486 | 0.84 | CHEK1 (0.83) | STK17ACHEK1FLT3KIT | |
| SCHEMBL3288718 | 0.84 | STK17A (0.91) | STK17ACHEK1FLT3STK17B | |
| SCHEMBL1917864 | 0.83 | STK17A (0.78) | STK17ACHEK1FLT3KITSTK17B | |
| SCHEMBL22508346 | 0.83 | STK17A (0.65) | STK17ASTK17B | |
| SCHEMBL21365058 | 0.82 | STK17A (0.78) | STK17ASTK17B | |
| SCHEMBL21364895 | 0.82 | STK17A (0.81) | STK17ASTK17B | |
| SCHEMBL28383014 | 0.81 | CHEK1 (1.00) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539951-B1 | NOVEL PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER AND INFLAMMATORY DISEASES | KOREA RES INST CHEMICAL TECH (KR) | 2020-10-07 | — | — | EP | disclosed |