Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCK1 | P16333 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22521518 | 0.82 | NPC1 (0.44) | ALDH1A1LMNAPOLBGAAKMT2A | |
| SCHEMBL29975503 | 0.81 | BACE1 (0.50) | BACE1CYP1A2ALDH1A1LMNAKMT2A | |
| SCHEMBL21129800 | 0.81 | BACE1 (0.50) | BACE1CYP1A2ALDH1A1LMNAKMT2A | |
| SCHEMBL13394489 | 0.79 | KMT2A (0.56) | CYP1A2ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL22521420 | 0.78 | SCN10A (0.37) | BACE1ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL22045308 | 0.78 | TLR8 (0.57) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL22509810 | 0.77 | CYP1A2 (0.52) | NCK1BACE1CYP1A2ALDH1A1LMNA | |
| SCHEMBL22521539 | 0.76 | TLR8 (0.40) | LMNAKMT2AMEN1SLC6A2HTR2B | |
| SCHEMBL13870796 | 0.75 | CYP1A2 (0.42) | NCK1BACE1CYP1A2ALDH1A1LMNA | |
| SCHEMBL22509740 | 0.74 | KMT2A (0.50) | NCK1BACE1CYP1A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205867-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |