Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.60 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22516600 | 0.93 | BRD4 (0.64) | BRD4 | |
| SCHEMBL22516420 | 0.93 | BRD4 (0.59) | BRD4 | |
| SCHEMBL22492875 | 0.88 | BRD4 (0.77) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL29977099 | 0.88 | BRD4 (0.77) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL22516425 | 0.87 | BRD4 (0.79) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL22516500 | 0.85 | BRD4 (0.78) | BRD4 | |
| SCHEMBL22516647 | 0.84 | BRD4 (0.60) | BRD4 | |
| SCHEMBL22516415 | 0.84 | BRD4 (0.58) | BRD4 | |
| SCHEMBL22516505 | 0.84 | BRD4 (0.68) | BRD4 | |
| SCHEMBL22516572 | 0.84 | BRD4 (0.66) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3719017-A2 | COMPOUND FUNCTIONING AS BROMODOMAIN PROTEIN INHIBITOR, AND COMPOSITION | Betta Pharmaceuticals Co., Ltd. (CN) | 2020-10-07 | — | — | EP | disclosed |