Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27258749 | 0.96 | EPHX2 (0.64) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL27029534 | 0.86 | EPHX2 (0.80) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL30445464 | 0.86 | EPHX2 (0.80) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL1456740 | 0.86 | EPHX2 (0.80) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL19043177 | 0.86 | EPHX2 (0.80) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL4183114 | 0.86 | EPHX2 (0.80) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL7426779 | 0.85 | EPHX2 (0.78) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL24095740 | 0.81 | EPHX2 (0.77) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL27404704 | 0.81 | HPGD (0.80) | EPHX2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL1285523 | 0.81 | HPGD (0.74) | EPHX2HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020201753-A1 | BICYCLE TOXIN CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-10-08 | — | — | WO | disclosed |